Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LSZ-102

LSZ-102 is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) with an IC50 value of 0.2 nM.

Product Specifications

CAS Number

2135600-76-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/LSZ-102.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/C1=CC=C(OC2=C(C3=CC=C(F)C=C3C(F)(F)C)SC4=CC(O)=CC=C42)C=C1

Molecular Formula

C25H17F3O4S

Molecular Weight

470.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Tria GS, et al. Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. J Med Chem. 2018 Apr 12;61 (7) :2837-2864.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

(2R,3R)-2-Ethyl-1,3-hexanediol
TRC-E193240-500MG 500 mg

(2R,3R)-2-Ethyl-1,3-hexanediol

Sign In for Pricing
View Details
6-Perdeoxy-6-perchloro-Gamma-cyclodextrin, >90%
TRC-P999728-50MG 50 mg

6-Perdeoxy-6-perchloro-Gamma-cyclodextrin, >90%

Sign In for Pricing
View Details
Anti Human SLC29A1 Polyclonal
Y055349 100 µL

Anti Human SLC29A1 Polyclonal

Sign In for Pricing
View Details
L1CAM Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2A11]
TA501436BM 100 µL

L1CAM Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2A11]

Sign In for Pricing
View Details
Human VPS37D activation kit by CRISPRa
GA115914 1 Kit

Human VPS37D activation kit by CRISPRa

Sign In for Pricing
View Details
Tissue FFPE Sections, Kidney
CS709918 5x 5 µm

Tissue FFPE Sections, Kidney

Sign In for Pricing
View Details