Belotecan
Product Specifications
UNSPSC Description
Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer[1].
Target Antigen
Apoptosis; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/belotecan.html
Smiles
O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CCNC(C)C)C5=CC=CC=C5N=C4C3=C2)=O
Molecular Weight
433.50
References & Citations
[1]Lee S, et al. CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer. Mol Med. 2019 May 28;25(1):23.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13566/Belotecan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13566/Belotecan-SDS-MedChemExpress.pdf
CAS Number
256411-32-2
Available Sizes
Curated Selection
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