BJJF078
BJJF078 is an aminopiperidine derivative. BJJF078 is a potent inhibitor of recombinant human and mouse Transglutaminase enzyme (TG2) activity, IC50 values of 41 and 54 nM, respectively. BJJF078 also inhibits the close related enzyme TG1, with an IC50 of 0.16 μM. BJJF078 can be used for Multiple sclerosis (MS) research[1].
Product Specifications
CAS Number
[2531244-56-9]
UNSPSC
12352005
Target
Glutaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bjjf078.html
Purity
99.34
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1CCN(S(=O)(C2=C3C=CC=C(NC(C4=CC=C(C(OC)=C4)OC)=O)C3=CC=C2)=O)CC1)C=C
Molecular Formula
C27H29N3O6S
Molecular Weight
523.60
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
PIAS2, GST-Tag, Recombinant (Miz, MIZ1, SIZ2, PIASX, ZMIZ4, MGC102682, PIASX-BETA, PIASX-ALPHA, DIP, MIZ, ARIP3, E3 SUMO-Protein Ligase PIAS2) discontinued
