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VUF-5574

Product Specifications

UNSPSC Description

VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].

Target Antigen

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/vuf-5574.html

Purity

99.41

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=C2C=CC=CC2=NC(C3=CC=CN=C3)=N1)NC4=CC=CC=C4OC

Molecular Weight

371.39

References & Citations

[1]van Muijlwijk-Koezen JE, et al. Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem. 2000 Jun 1;43(11):2227-38.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-103189/VUF-5574-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-103189/VUF-5574-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

280570-45-8

Available Sizes

Curated Selection

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