VUF-5574
VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].
Product Specifications
CAS Number
[280570-45-8]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vuf-5574.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=C2C=CC=CC2=NC(C3=CC=CN=C3)=N1)NC4=CC=CC=C4OC
Molecular Formula
C21H17N5O2
Molecular Weight
371.39
References & Citations
[1]van Muijlwijk-Koezen JE, et al. Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A (3) receptor. J Med Chem. 2000 Jun 1;43 (11) :2227-38.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A3 receptor (A3R)
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1185625-01 0.02 mg (E-Coli)
Recombinant Neisseria gonorrhoeae Probable nicotinate-nucleotide adenylyltransferase (nadD)
Ask
View Details MBS1185625-02 0.1 mg (E-Coli)
Recombinant Neisseria gonorrhoeae Probable nicotinate-nucleotide adenylyltransferase (nadD)
Ask
View Details 
MBS1185625-03 0.02 mg (Yeast)
Recombinant Neisseria gonorrhoeae Probable nicotinate-nucleotide adenylyltransferase (nadD)
Ask
View Details 
MBS1185625-04 0.1 mg (Yeast)
Recombinant Neisseria gonorrhoeae Probable nicotinate-nucleotide adenylyltransferase (nadD)
Ask
View Details 
MBS1185625-05 0.02 mg (Baculovirus)
Recombinant Neisseria gonorrhoeae Probable nicotinate-nucleotide adenylyltransferase (nadD)
Ask
View Details MBS1185625-06 0.02 mg (Mammalian-Cell)
Recombinant Neisseria gonorrhoeae Probable nicotinate-nucleotide adenylyltransferase (nadD)
Ask
View Details