AzGGK (TFA)
AzGGK TFA is an unnatural amino acid. AzGGK TFA is site-specifically incorporated into proteins via genetic-code expansion. AzGGK TFA can be used as a site-specific probe for ubiquitylation and SUMOylation. AzGGK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1].
Product Specifications
UNSPSC
12352209
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/azggk-tfa.html
Purity
99.77
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
[N-]=[N+]=NCC(NCC(NCCCC[C@H](N)C(O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C12H19F3N6O6
Molecular Weight
400.31
References & Citations
[1]Fottner M, et al. Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase. Nat Chem Biol. 2019 Mar;15 (3) :276-284.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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