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AzGGK (TFA)

AzGGK TFA is an unnatural amino acid. AzGGK TFA is site-specifically incorporated into proteins via genetic-code expansion. AzGGK TFA can be used as a site-specific probe for ubiquitylation and SUMOylation. AzGGK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1].

Product Specifications

UNSPSC

12352209

Target

Fluorescent Dye

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/azggk-tfa.html

Purity

99.77

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NCC(NCC(NCCCC[C@H](N)C(O)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C12H19F3N6O6

Molecular Weight

400.31

References & Citations

[1]Fottner M, et al. Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase. Nat Chem Biol. 2019 Mar;15 (3) :276-284.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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