5-Bromo-3-phenyl salicylic acid
Selected Variant
HY-118819-01
Size: 1 mg
5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 140 nM[1].
Product Specifications
CAS Number
99514-99-5
Product Name Alternative
AMD 3100; JM3100; SID791
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-bromo-3-phenyl-salicylic-acid.html
Purity
98.00
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(Br)=CC(C2=CC=CC=C2)=C1O)O
Molecular Formula
C13H9BrO3
Molecular Weight
293.11
Precautions
H302, H315, H319, H335
References & Citations
[1]El-Kabbani O, et al., Structure-guided design, synthesis, and evaluation of salicylic acid-based inhibitors targeting a selectivity pocket in the active site of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) . J Med Chem. 2009 May 28;52 (10) :3259-64.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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Price
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