AZD8701
AZD8701 (IONIS-1063734) is an antisense oligonucleotide targeting FOXP3 in regulatory T cells (Tregs) . AZD8701 can relieve immunosuppression in cancer[1].
Product Specifications
CAS Number
2603457-08-3
Product Name Alternative
IONIS-1063734
UNSPSC
12352208
Target
TGF-beta/Smad
Type
Oligonucleotides
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/azd8701.html
Smiles
[AZD8701]
References & Citations
[1]Alexey Revenko, et al. Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer. J Immunother Cancer. 2022 Apr;10 (4) :e003892.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 1
Frequently Asked Questions
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