AZD8701
Product Specifications
UNSPSC Description
AZD8701 (IONIS-1063734) is an antisense oligonucleotide targeting FOXP3 in regulatory T cells (Tregs). AZD8701 can relieve immunosuppression in cancer[1].
Target Antigen
TGF-beta/Smad
Type
Oligonucleotides
Related Pathways
Stem Cell/Wnt;TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/azd8701.html
Smiles
[AZD8701]
References & Citations
[1]Alexey Revenko, et al. Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer. J Immunother Cancer. 2022 Apr;10(4):e003892.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159692/AZD8701-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159692/
Clinical Information
Phase 1
CAS Number
2603457-08-3
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