AZD8701

AZD8701 (IONIS-1063734) is an antisense oligonucleotide targeting FOXP3 in regulatory T cells (Tregs) . AZD8701 can relieve immunosuppression in cancer[1].

Product Specifications

CAS Number

[2603457-08-3]

Product Name Alternative

IONIS-1063734

UNSPSC

12352208

Target

TGF-beta/Smad

Type

Oligonucleotides

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/azd8701.html

Smiles

[AZD8701]

References & Citations

[1]Alexey Revenko, et al. Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer. J Immunother Cancer. 2022 Apr;10 (4) :e003892.