Moricizine-d8 (Hydrochloride)
Moricizine-d8 Hydrochloride is the deuterium labeled Moricizine Hydrochloride. Moricizine Hydrochloride is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period[1][2].
Product Specifications
CAS Number
2300178-76-9
Product Name Alternative
EN 313-d8; Ethmozin-d8; Moracizine-d8
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
[2H]C1([2H])C([2H])([2H])OC([2H])([2H])C([2H])([2H])N1CCC(N2C3=CC(NC(OCC)=O)=CC=C3SC4=CC=CC=C42)=O.Cl
Molecular Formula
C22H18D8ClN3O4S
Molecular Weight
472.03
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Bigger JT Jr. Cardiac electrophysiologic effects of moricizine hydrochloride. Am J Cardiol. 1990 Feb 20;65 (8) :15D-20D; discussion 68D-71D.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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