Nrf2 activator-1
Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2) . Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1) [1].
Product Specifications
CAS Number
2230697-41-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Keap1-Nrf2
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nrf2-activator-1.html
Purity
98.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC(C[C@@H](C1=CC(CN2S(=O)(C3=CC=CC=C3O[C@@H](C2)C)=O)=C(C=C1)C)C4=CC(OC)=C(N(N=N5)C)C5=C4)=O
Molecular Formula
C30H34N4O6S
Molecular Weight
578.68
Precautions
H302, H315, H319
References & Citations
[1]James Francis Callahan, et al. Bisaryl amides as nrf2 regulators. Patent WO2018109647A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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