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Nrf2 activator-1

Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2) . Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1) [1].

Product Specifications

CAS Number

[2230697-41-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nrf2-activator-1.html

Purity

98.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCOC(C[C@@H](C1=CC(CN2S(=O)(C3=CC=CC=C3O[C@@H](C2)C)=O)=C(C=C1)C)C4=CC(OC)=C(N(N=N5)C)C5=C4)=O

Molecular Formula

C30H34N4O6S

Molecular Weight

578.68

Precautions

H302, H315, H319

References & Citations

[1]James Francis Callahan, et al. Bisaryl amides as nrf2 regulators. Patent WO2018109647A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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