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BA 1

BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].

Product Specifications

CAS Number

183241-31-8

UNSPSC

12352209

Target

Bombesin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ba-1.html

Solubility

H2O

Smiles

O=C(CCNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](N)CC1=CC=C(O)C=C1)=O)CCC(N)=O)=O)CC2=CNC3=CC=CC=C23)=O)C)=O)C(C)C)=O)N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCC)=O)CC4=CC=CC=C4)=O)CC5=CNC=N5

Molecular Formula

C57H76N14O11

Molecular Weight

1133.30

References & Citations

[1]Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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