Viomellein
Viomellein is a SUMOylation inhibitor with antibacterial and anticancer activities. Viomellein inhibits biofilm formation of strains produced from the fungus Aspergillus ochraceus from the Mediterranean sponge Agelas oroides. Viomellein exhibits cytotoxicity against A2780 human ovarian cancer cells with an IC50 value of 5.0 μM. Viomellein also inhibits SUMOylation of RanGAP1 (GTPase activating protein) with an IC50 of 10.2 μM[1][2][3].
Product Specifications
CAS Number
[55625-78-0]
UNSPSC
12352005
Target
Bacterial; E1/E2/E3 Enzyme
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/viomellein.html
Smiles
O=C1C2=C(O)C3=C(C(C(OC)=C(C4=C(OC)C=C5C=C(C[C@@H](C)O6)C(C6=O)=C(O)C5=C4O)C3=O)=O)C=C2C[C@@H](C)O1
Molecular Formula
C30H24O11
Molecular Weight
560.50
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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