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Loratadine-d5-1

Loratadine-d5-1 is a deuterated labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.

Product Specifications

CAS Number

1020719-57-6

Product Name Alternative

Loratidine-d5-1; SCH 29851-d5-1

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Others

Smiles

O=C(N1CC/C(CC1)=C2C3=CC=C(Cl)C=C3CC([2H])([2H])C4=C([2H])C([2H])=C([2H])N=C4\2)OCC

Molecular Formula

C22H18D5ClN2O2

Molecular Weight

387.91

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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