Loratadine-d5-1
Loratadine-d5-1 is a deuterated labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
Product Specifications
CAS Number
1020719-57-6
Product Name Alternative
Loratidine-d5-1; SCH 29851-d5-1
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Smiles
O=C(N1CC/C(CC1)=C2C3=CC=C(Cl)C=C3CC([2H])([2H])C4=C([2H])C([2H])=C([2H])N=C4\2)OCC
Molecular Formula
C22H18D5ClN2O2
Molecular Weight
387.91
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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