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Lucidin

Lucidin (NSC 30546) is a natural component of madder and can induce mutations in bacterial and mammalian cells.

Product Specifications

CAS Number

[478-08-0]

Product Name Alternative

NSC 30546

UNSPSC

12352005

Hazard Statement

H302, H351

Target

Apoptosis; Caspase; HPV

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lucidin.html

Purity

98.03

Solubility

DMSO : 6.67 mg/mL (ultrasonic)

Smiles

O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(CO)C(O)=C13)=O

Molecular Formula

C15H10O5

Molecular Weight

270.24

Precautions

H302, H351

References & Citations

[1]Westendorf J, et al. The genotoxicity of lucidin, a natural component of Rubia tinctorum L., and lucidinethylether, a component of ethanolic Rubia extracts. Cell Biol Toxicol. 1988 Jun;4 (2) :225-39.|[2]Westendorf J, et al. Carcinogenicity and DNA adduct formation observed in ACI rats after long-term treatment with madder root, Rubia tinctorum L. Carcinogenesis. 1998 Dec;19 (12) :2163-8.|[3]Gomes D, et al., Taxifolin and Lucidin as Potential E6 Protein Inhibitors: p53 Function Re-Establishment and Apoptosis Induction in Cervical Cancer Cells. Cancers (Basel) . 2022 Jun 8;14 (12) :2834.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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