HVEGF-IN-3
HVEGF-IN-3 (compound 9) is a potent hVEGF inhibitor. hVEGF-IN-3 inhibits HT-29, MCF-7, and HEK-293 cells proliferation with IC50s of 61, 142, and 114 μM[1].
Product Specifications
CAS Number
[46739-60-0]
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hvegf-in-3.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC(C=C1)=CC=C1/C=C/C2=CC=NC=C2
Molecular Formula
C14H13NO
Molecular Weight
211.26
References & Citations
[1]Martí-Centelles R, et al. Inhibitory effect of cytotoxic nitrogen-containing heterocyclic stilbene analogues on VEGF protein secretion and VEGF, hTERT and c-Myc gene expression[J]. MedChemComm, 2015, 6 (10) : 1809-1815.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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