15-Acetoxyscirpenol

15-acetoxyscirpenol, one of acetoxyscirpenol moiety mycotoxins (ASMs), strongly induces apoptosis and inhibits Jurkat T cell growth in a dose-dependent manner by activating other caspases independent of caspase-3[1].

Product Specifications

CAS Number

[2623-22-5]

UNSPSC

12352005

Hazard Statement

H301

Target

Antibiotic; Apoptosis; Bacterial; Caspase

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/15-acetoxyscirpenol.html

Purity

99.35

Solubility

10 mM in DMSO|DMSO : ≥ 30mg/mL

Smiles

CC([C@]1(CC2)COC(C)=O)([C@@H]3O)C4(CO4)[C@@](O[C@]1([H])C=C2C)([H])[C@@H]3O

Molecular Formula

C17H24O6

Molecular Weight

324.37

Precautions

P264-P270-P330-P405-P501

References & Citations

[1]Lee DH, et al. Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins. Biol Pharm Bull. 2006 Apr;29 (4) :648-54.