Z-Leu-Arg-AMC
Z-Leu-Arg-AMC is a 4-methylcoumarinyl-7-amide (Amc) leucine derivative with carboxybenzoyl (Z) . Z-Leu-Arg-AMC is the active site of cysteine proteinase trypanopain-Tb from Trypanosoma brucei brucei[1].
Product Specifications
CAS Number
156192-32-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/z-leu-arg-amc.html
Concentration
10mM
Purity
99.24
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)C=C1O3)=CC3=O
Molecular Formula
C30H38N6O6
Molecular Weight
578.66
References & Citations
[1]Troeberg L, et al. Production of anti-peptide antibodies against trypanopain-Tb from Trypanosoma brucei brucei: effects of antibodies on enzyme activity against Z-Phe-Arg-AMC. Immunopharmacology. 1997 Jun;36 (2-3) :295-303.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Trypanosoma
Available Sizes
Frequently Asked Questions
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