Z-Leu-Arg-AMC

Z-Leu-Arg-AMC is a 4-methylcoumarinyl-7-amide (Amc) leucine derivative with carboxybenzoyl (Z) . Z-Leu-Arg-AMC is the active site of cysteine proteinase trypanopain-Tb from Trypanosoma brucei brucei[1].

Product Specifications

CAS Number

[156192-32-4]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/z-leu-arg-amc.html

Concentration

10mM

Purity

99.24

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)C=C1O3)=CC3=O

Molecular Formula

C30H38N6O6

Molecular Weight

578.66

References & Citations

[1]Troeberg L, et al. Production of anti-peptide antibodies against trypanopain-Tb from Trypanosoma brucei brucei: effects of antibodies on enzyme activity against Z-Phe-Arg-AMC. Immunopharmacology. 1997 Jun;36 (2-3) :295-303.