IDO-IN-8
IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.
Product Specifications
CAS Number
[1402837-77-7]
Product Name Alternative
NLG-1487
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO-IN-8.html
Purity
99.99
Solubility
Ethanol : 100 mg/mL (ultrasonic)
Smiles
O[C@H](CC1)CC[C@]1([H])[C@@H](O)C[C@H]2N3C(C4=C2C(F)=CC=C4)=CN=C3
Molecular Formula
C18H21FN2O2
Molecular Weight
316.37
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO
Available Sizes
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