LysoSensor PDMPO
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) [1].
Product Specifications
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lysosensor-pdmpo.html
Purity
98.77
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCCN(C)C)COC(C=C1)=CC=C1C2=CN=C(O2)C3=CC=NC=C3
Molecular Formula
C20H22N4O3
Molecular Weight
366.41
References & Citations
[1]L V Albrecht, et al. Protocol for Probing Regulated Lysosomal Activity and Function in Living Cells. STAR Protoc. 2020 Oct 17;1 (3) :100132.|[2]Patricia Merdy, et al. PDMPO: a specific silicon or silica, pH sensitive fluorescent probe? RSC Adv. 2020 Aug 21;10 (51) :31003-31011.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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