RXR antagonist 5
RXR antagonist 5 (compound 22) is a selective retinoic acid X receptor (RXR) antagonist with binding potential to RXR evaluated by modeling.
Product Specifications
CAS Number
[1807740-94-8]
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rxr-antagonist-5.html
Purity
98.80
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CN=C(N(CC)C2=C(C)C=C(C(C)(CCC3(C)C)C)C3=C2)C=C1)O
Molecular Formula
C23H30N2O2
Molecular Weight
366.50
References & Citations
[1]Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR) -Selective Agonists: Analogues of 4-[1- (3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl) ethynyl]benzoic Acid (Bexarotene) and 6- (Ethyl (5,5,8,8-tetrahydronaphthalen-2-yl) amino) nicotinic Acid (NEt-TMN)
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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