RXR antagonist 5

RXR antagonist 5 (compound 22) is a selective retinoic acid X receptor (RXR) antagonist with binding potential to RXR evaluated by modeling.

Product Specifications

CAS Number

[1807740-94-8]

UNSPSC

12352005

Target

RAR/RXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rxr-antagonist-5.html

Purity

98.80

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CN=C(N(CC)C2=C(C)C=C(C(C)(CCC3(C)C)C)C3=C2)C=C1)O

Molecular Formula

C23H30N2O2

Molecular Weight

366.50

References & Citations

[1]Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR) -Selective Agonists: Analogues of 4-[1- (3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl) ethynyl]benzoic Acid (Bexarotene) and 6- (Ethyl (5,5,8,8-tetrahydronaphthalen-2-yl) amino) nicotinic Acid (NEt-TMN)