COX-2-IN-39
COX-2-IN-39 (compound 44) is a potent inhibitor of COX-2, with the IC50 value of 0.4 nM[1].
Product Specifications
CAS Number
1018480-89-1
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cox-2-in-39.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C2=NC(OC)=CC(NCC3=CC=CS3)=N2)C=C1)(C)=O
Molecular Formula
C17H17N3O3S2
Molecular Weight
375.47
References & Citations
[1]Aurelio Orjales, et al. Hansch analysis of novel pyrimidine derivatives as highly potent and specific COX-2 inhibitors. Bioorg Med Chem. 2008 Mar 1;16 (5) :2183-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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