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αA-Conotoxin PIVA

Product Specifications

CAS Number

171439-59-1

UNSPSC Description

αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. αA-Conotoxin PIVA can be used in the study of neurological diseases.

Target Antigen

nAChR

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

[GCCGSY-{Hyp}-NAACH-{Hyp}-CSCKDR-{Hyp}-SYCGQ-NH2(Disulfidebridge:Cys2-Cys16,Cys3-Cys11,Cys14-Cys23)]

Molecular Weight

2648.89

References & Citations

[1]Teichert RW, et al. Definition and characterization of the short alphaA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor. Biochemistry. 2006 Jan 31;45(4):1304-12.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

Frequently Asked Questions

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