D- (-) -Pantolactone

D- (-) -Pantolactone is an important intermediate that can be used in the synthesis of other active compounds, such as the molluscicide Cyanolide A. D- (-) -Pantolactone is also a calibrant for circular dichroism (CD) [1][2][3].

Product Specifications

CAS Number

[599-04-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Drug Intermediate; Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pantolactone.html

Concentration

10mM

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1OCC(C)(C)[C@H]1O

Molecular Formula

C6H10O3

Molecular Weight

130.14

Precautions

H302, H315, H319, H335

References & Citations

[3]Fang H, et al. Synthesis, biological activities, and docking studies of d-pantolactone derivatives as novel FAS inhibitors. Bioorg Med Chem. 2019 Oct 15;27 (20) :115069.|[1]Hajare AK, et al. Synthesis of molluscicidal agent cyanolide a macrolactone from D- (-) -pantolactone. J Org Chem. 2011 Feb 4;76 (3) :963-6.|[2]Konno T, et al. D-pantolactone as a circular dichromism (CD) calibration. Anal Biochem. 1975 Jul;67 (1) :226-32.