D- (-) -Pantolactone
D- (-) -Pantolactone is an important intermediate that can be used in the synthesis of other active compounds, such as the molluscicide Cyanolide A. D- (-) -Pantolactone is also a calibrant for circular dichroism (CD) [1][2][3].
Product Specifications
CAS Number
599-04-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents; Drug Intermediate; Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pantolactone.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1OCC(C)(C)[C@H]1O
Molecular Formula
C6H10O3
Molecular Weight
130.14
Precautions
H302, H315, H319, H335
References & Citations
[3]Fang H, et al. Synthesis, biological activities, and docking studies of d-pantolactone derivatives as novel FAS inhibitors. Bioorg Med Chem. 2019 Oct 15;27 (20) :115069.|[1]Hajare AK, et al. Synthesis of molluscicidal agent cyanolide a macrolactone from D- (-) -pantolactone. J Org Chem. 2011 Feb 4;76 (3) :963-6.|[2]Konno T, et al. D-pantolactone as a circular dichromism (CD) calibration. Anal Biochem. 1975 Jul;67 (1) :226-32.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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