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Mouse IRAK4 Protein, His Tag (active enzyme)

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

Background

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 52.9 kDa.

Accession Number

Q8R4K2-1

Expression Region

Met 1 - Ala 459

Host

Insect Cells

Target

IRAK4

Conjugation

Unconjugated

Tag

N-10xHis

Source

Mouse

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Format

Liquid

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Additives

Glycerol

Molecular Weight

52.9 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Host or Source

InsectCells

Species

Mouse

Protein ID

Q8R4K2-1

Preservative

Glycerol

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