α-Conotoxin MrIC
Product Specifications
UNSPSC Description
α-Conotoxin MrIC is an α7nAChR biased agonist. α-Conotoxin MrIC exclusively activates α7nAChR regulated by type II positive allosteric modulators, including PNU120596. α-Conotoxin MrIC can be used to study neurological diseases and also to probe the pharmacological properties of α7nAChR[1].
Target Antigen
nAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C1N2[C@@](CCC2)(C(=O)N[C@@H](C)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N5[C@](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(N)=O)CSSC[C@@](C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@H]1CC6=CN=CN6)[H])(NC(=O)[C@@H](NC([C@@H](NC(=O)[C@@H]7CCCN7)CCC(O)=O)=O)CSSC3)[H])(CCC5)[H])[H])[H]
Molecular Weight
1835.07
References & Citations
[1]Mueller A, et al. α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochem Pharmacol. 2015 Mar 15;94(2):155-63.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
1417816-41-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![QPRT Mouse Monoclonal Antibody [Clone ID: OTI1C10]](https://cdn.genprice.uk/genprice/genprice4.png)
