PROTAC AR Degrader-4 (TFA)
PROTAC AR Degrader-4 comprises a IAP ligand binding group, a linker and an Androgen Receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs) [1].
Product Specifications
UNSPSC
12352005
Target
Androgen Receptor; PROTACs; SNIPERs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-ar-degrader-4-tfa.html
Purity
99.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
Molecular Formula
C45H68F3N3O11
Molecular Weight
884.03
References & Citations
[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19 (22) :6768-78.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CIAP1
Available Sizes
Frequently Asked Questions
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