β-Amanitin
β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) [1][2].
Product Specifications
CAS Number
21150-22-1
UNSPSC
12352203
Hazard Statement
H300+H310+H330
Target
ADC Payload; DNA/RNA Synthesis
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/β-amanitin.html
Purity
96.0
Solubility
DMSO : 20 mg/mL (ultrasonic) |H2O : ≥ 10 mg/mL
Smiles
Molecular Formula
C39H53N9O15S
Molecular Weight
919.95
Precautions
P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Filaggrin (Keratinocyte Differentiation Marker) (FLG/1945), 0.2mg/mL
Cytokeratin, Multi (Epithelial Marker) (rKRT/457), 1mg/mL
