VU0155094
Product Specifications
Product Name Alternative
ML397
UNSPSC Description
VU0155094 is a positive allosteric modulator with differential activity at the various group III mGluRs[1].
Target Antigen
mGluR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0155094.html
Purity
98.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)C1=CC=C(N2C(C)=C(C(CSC3=CC=C(NC(C)=O)C=C3)=O)C=C2C)C=C1
Molecular Weight
436.52
References & Citations
[1]Jalan-Sakrikar N, et al. Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121848/VU0155094-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121848/VU0155094-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
731006-86-3
Available Sizes
Curated Selection
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