HIV-1 inhibitor-66
Product Specifications
UNSPSC Description
HIV-1 inhibitor-66 is an orally active non-nucleoside reverse transcription inhibitor (NNRTI). HIV-1 inhibitor-66 shows inhibitory activity against wild-type HIV-1 reverse transcriptase with an IC50 of 40 nM[1].
Target Antigen
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-66.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C=CC(C(F)(F)F)=C1OC2=CC(C3=CC=C(C=C3)Br)=CC(Cl)=C2)CC4=NNC(N4C)=O
Molecular Weight
555.73
References & Citations
[1]Yanying Sun, et al. Discovery of Novel Aryl Triazolone Dihydropyridines (ATDPs) Targeting Highly Conserved Residue W229 as Promising HIV-1 NNRTIs. J Med Chem. 2024 Apr 25;67(8):6570-6584.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162461/HIV-1-inhibitor-66-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162461/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
6ERV11-03PPCT 1000 / Pack
SureSTART 0.3mL Polypropylene Snap Top Vials with Fixed Inserts Level 1
Ask
View Details 
