2',3'-Dideoxyadenosine
2',3'-Dideoxyadenosine is an inhibitor of HIV replication[1]. Antiretroviral activity[1]. Antiviral efficacy[1].
Product Specifications
CAS Number
[4097-22-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/2_acute_,3_acute_-Dideoxyadenosine.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC[C@@H]1CC[C@H](N2C(N=CN=C3N)=C3N=C2)O1
Molecular Formula
C10H13N5O2
Molecular Weight
235.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Balzarini J, et al. Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus. FEBS Lett. 1997 Jun 30;410 (2-3) :324-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1; HIV-2
Available Sizes
Curated Selection
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