Curcumin 5-8

Curcumin 5-8 (CUR5-8) is a potent and orally active naturally active curcumin (CUR) analog. Curcumin 5-8 inhibits lipid droplet formation. Curcumin 5-8 increases autophagy and inhibits Apoptosis. Curcumin 5-8 improves insulin resistance and insulin sensitivity[1].

Product Specifications

CAS Number

[890984-26-6]

Product Name Alternative

CUR5-8

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy

Type

Natural Products

Related Pathways

Apoptosis; Autophagy

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/curcumin-5-8.html

Concentration

10mM

Purity

98.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(NC(C(C)C)=O)=CC=C1)/C=C/C2=CC=C(C(OC)=C2)O

Molecular Formula

C20H21NO4

Molecular Weight

339.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Lee ES, et al. Curcumin analog CUR5-8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity. Metabolism. 2020 Feb;103:154015.