AUTEN-67
AUTEN-67 (Autophagy enhancer-67) is an orally active autophagy enhancer and MTMR14 inhibitor. AUTEN-67 has anti-aging and neuroprotective effects. AUTEN-67 protects neurons from stress-induced cell death. AUTEN-67 also restores nesting behavior in a mice model of Alzheimer disease[1].
Product Specifications
CAS Number
[1783800-77-0]
Product Name Alternative
Autophagy enhancer-67
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/auten-67.html
Purity
97.14
Solubility
DMSO : 11.9 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C([N+]([O-])=O)C=C1)(NC(C2=O)=C(N3C4=CC=CC=C4N=C3)C(C5=C2C=CC=C5)=O)=O
Molecular Formula
C23H14N4O6S
Molecular Weight
474.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Papp D, et al. AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects. Autophagy. 2016;12 (2) :273-86.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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