ZINC08438472
ZINC08438472 is a potent and selective peroxisome proliferator activated receptors-α (PPAR-α) agonist with an EC50 value of 12.1 nM. ZINC08438472 is promising for research of diabetes, hyperlipidaemia and inflammatory disorders[1].
Product Specifications
CAS Number
443872-20-6
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/zinc08438472.html
Smiles
O=C(C(C/1=O)=C(NC2=CC=C(OCC)C=C2)SC1=C\C3=CC=C(OCC(O)=O)C(OC)=C3)OCC
Molecular Formula
C25H25NO8S
Molecular Weight
499.53
References & Citations
[1]Gangwal RP, et al. Biological evaluation and structural insights for design of subtype-selective peroxisome proliferator activated receptor-α (PPAR-α) agonists. Bioorg Med Chem Lett. 2015 Jan 15;25 (2) :270-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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