Stevisalioside A
Product Specifications
CAS Number
142934-44-9
UNSPSC Description
Stevisalioside A (Compound 2) can be isolated from Stevia serrata roots. Stevisalioside A is an orally active antidiabetic agent. Stevisaliosides A inhibits PTP1B (IC50: 526.8 μM). Stevisalioside A reduces blood glucose levels and the postprandial peak in oral glucose and insulin tolerance tests in Streptozotocin (HY-13753) induced hyperglycemic mice[1].
Target Antigen
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/stevisalioside-a.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC([C@@]3(C)[C@](CC[C@@](C4)(C5)[C@@]6([H])[C@@H](O)[C@H](C5=O)C4=C)([H])[C@@]6(C)CCC3)=O)O[C@@H]2CO)OC1
Molecular Weight
710.76
References & Citations
[1]Padilla-Mayne S, et al. Chemical Analysis and Antidiabetic Potential of a Decoction from Stevia serrata Roots. J Nat Prod. 2023 Sep 22.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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