Prepro-TRH- (160-169)
Prepro-TRH- (160-169) is one of the connecting peptides of thyrotropin-releasing hormone prohormone (pro-TRH), potentiates TRH-induced thyrotropin (TSH) release[1].
Product Specifications
CAS Number
122018-91-1
UNSPSC
12352209
Target
Thyroid Hormone Receptor
Type
Peptides
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/prepro-trh-160-169.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCC1)C([C@@H](NC([C@@H](N)CO)=O)CC2=CC=CC=C2)=O)N[C@H](C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)[C@H](O)C)=O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34
Molecular Formula
C54H75N11O18S
Molecular Weight
1198.30
References & Citations
[1]H Yang, et al. Prepro-TRH- (160-169) potentiates gastric acid secretion stimulated by TRH microinjected into the dorsal motor nucleus of the vagus. Neurosci Lett. 1994 Jun 6;174 (1) :43-6.|[2]J P Roussel, et al. Somatostatin blocks the potentiation of TRH-induced TSH secretion from perifused pituitary fragments and the change in intracellular calcium concentrations from dispersed pituitary cells elicited by prepro-TRH (PS4) or by tri-iodothyronine. J Mol Endocrinol. 1997 Aug;19 (1) :87-97.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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