Gabazine
Gabazine is a selective and competitive antagonist of GABAA receptor, with an IC50 of ~0.2 μM for GABA receptor.
Product Specifications
CAS Number
[104104-50-9]
Product Name Alternative
SR95531
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Gabazine.html
Purity
98.72
Solubility
DMSO : ≥ 75 mg/mL|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CCCN1C(C=CC(C2=CC=C(OC)C=C2)=N1)=N.[H]Br
Molecular Formula
C15H18BrN3O3
Molecular Weight
368.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Ueno S, et al. Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor. J Neurosci. 1997 Jan 15;17 (2) :625-34.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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