Cbl-b-IN-12

Cbl-b-IN-12 (Example 10) is a casitas B-lineage lymphoma-b (CBL-B) inhibitor with an IC50 of [1].

Product Specifications

CAS Number

[2851871-29-7]

UNSPSC

12352005

Target

E1/E2/E3 Enzyme

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cbl-b-in-12.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C2=CC=CC(C3(CC4=NN=CN4C)COC3)=C2)C=C5C(C(F)(F)F)=CC(CN6CCC7(CC7)C6)=CN15

Molecular Formula

C28H29F3N6O2

Molecular Weight

538.56

References & Citations

[1]Yingzhi Bi, et al. Compounds, compositions and methods of treating cancer. Patent WO2022221704A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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