Cbl-b-IN-12
Cbl-b-IN-12 (Example 10) is a casitas B-lineage lymphoma-b (CBL-B) inhibitor with an IC50 of [1].
Product Specifications
CAS Number
[2851871-29-7]
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbl-b-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC=CC(C3(CC4=NN=CN4C)COC3)=C2)C=C5C(C(F)(F)F)=CC(CN6CCC7(CC7)C6)=CN15
Molecular Formula
C28H29F3N6O2
Molecular Weight
538.56
References & Citations
[1]Yingzhi Bi, et al. Compounds, compositions and methods of treating cancer. Patent WO2022221704A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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