ERAP1-IN-1

ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1].

Product Specifications

CAS Number

[865273-97-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335, H413

Target

Aminopeptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/erap1-in-1.html

Purity

98.77

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)C1=CC=C(OC)C(S(=O)(NC2=CC(C(F)(F)F)=CC=C2N3CCCCC3)=O)=C1

Molecular Formula

C20H21F3N2O5S

Molecular Weight

458.45

Precautions

H302, H315, H319, H335, H413

References & Citations

[1]Maben Z, et al. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. J Med Chem. 2019 Dec 30.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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