α‑Amylase-IN-1
α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1]
Product Specifications
CAS Number
[148404-10-8]
UNSPSC
12352005
Target
Amylases
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-amylase-in-1-1.html
Purity
98.33
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C2=NN(C(C)=O)C(C3=CC=C(OC)C=C3)C2)C=C1
Molecular Formula
C18H18N2O3
Molecular Weight
310.35
References & Citations
[1]Ali A, et al. Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies. ACS Omega. 2023 Jun 2;8 (23) :20412-20422.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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