What is the catalog number for AGI-5198?

The catalog number for AGI-5198 is HY-18082.

What sizes are available for AGI-5198?

AGI-5198 is available in the following size(s): 5 mg, 10 mg, 10 mM - 1 mL, 50 mg, 100 mg, 200 mg, 500 mg, 1 g.

How many pack sizes does AGI-5198 come in?

AGI-5198 is available in 8 different pack sizes.

Is AGI-5198 in stock?

AGI-5198 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AGI-5198?

AGI-5198 is manufactured by QuantiMol.

What is the estimated delivery time for AGI-5198?

Estimated delivery time for AGI-5198 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AGI-5198?

The safety data sheet for AGI-5198 is available here: http://file.medchemexpress.com/batch_PDF/HY-18082/AGI-5198-SDS-MedChemExpress.pdf.

AGI-5198

AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor with an IC50 of 0.07 μM.

Product Specifications

CAS Number

1355326-35-0

Product Name Alternative

IDH-C35

UNSPSC

12352005

Hazard Statement

H301

Target

Isocitrate Dehydrogenase (IDH)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/AGI-5198.html

Purity

99.93

Solubility

DMF : ≥ 50 mg/mL|DMSO : 20.83 mg/mL (ultrasonic)

Smiles

FC1=CC=CC(N(C(C2=CC=CC=C2C)C(NC3CCCCC3)=O)C(CN4C=CN=C4C)=O)=C1

Molecular Formula

C27H31FN4O2

Molecular Weight

462.56

Precautions

H301

References & Citations

[1]Rohle D, et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science. 2013 May 3;340 (6132) :626-30.|[2]Molenaar RJ, et al. Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198. Cancer Res. 2015 Nov 15;75 (22) :4790-802.