NEU3-IN-1
NEU3-IN-1 (compound 963) is a NEU3 inhibitor (Ki: 0.12 μM; IC50: 0.31 μM) based on the 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) scaffold and is a C9 biphenylcarbamate derivative. NEU is a human neuraminidase with 4 isozymes; NEU3-IN-1 is an important tool for studying the function of NEU3 isozymes; its amide and triazole linker analogs are selective for NEU1 and NEU4 isozymes, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neu3-in-1.html
Smiles
O[C@H]([C@H](O)COC(NC1=CC=C(C2=CC=CC=C2)C=C1)=O)[C@]3([C@H](NC(C)=O)[C@@H](O)C=C(C(O)=O)O3)[H]
Molecular Formula
C24H26N2O9
Molecular Weight
486.47
References & Citations
[1]Bioisosteres at C9 of 2-Deoxy-2,3-didehydro-N-acetyl Neuraminic Acid Identify Selective Inhibitors of NEU
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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