GSK-7227
GSK-7227 (compound 32) is a PPARδ partial agonist with the activity of regulating the expression of related genes. GSK-7227 has partial agonist effects on PPARδ target genes CPT1a and PDK4 in skeletal muscle cells.
Product Specifications
CAS Number
1067214-81-6
UNSPSC
12352005
Target
PDHK; PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gsk-7227.html
Smiles
O=C(C1=CC(C)=CC=C1NC(C2=CC=CC(S(=O)(N3C=CC4=C(C)C(OC)=CC=C43)=O)=C2)=O)O
Molecular Formula
C25H22N2O6S
Molecular Weight
478.52
References & Citations
[1]Discovery of a novel class of PPARδ partial agonists
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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