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GSK-7227

GSK-7227 (compound 32) is a PPARδ partial agonist with the activity of regulating the expression of related genes. GSK-7227 has partial agonist effects on PPARδ target genes CPT1a and PDK4 in skeletal muscle cells.

Product Specifications

CAS Number

1067214-81-6

UNSPSC

12352005

Target

PDHK; PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/gsk-7227.html

Smiles

O=C(C1=CC(C)=CC=C1NC(C2=CC=CC(S(=O)(N3C=CC4=C(C)C(OC)=CC=C43)=O)=C2)=O)O

Molecular Formula

C25H22N2O6S

Molecular Weight

478.52

References & Citations

[1]Discovery of a novel class of PPARδ partial agonists

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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